Endocrine Abstracts

In developed countries, prostate cancer (PCa) is the most prevalent cancer and the second most common cause of cancer related death in males. Tumors from patients exhibiting disease progression after systemic androgen deprivation treatment (ADT), referred to as castration resistant prostate cancer (CRPC), often show differentiation towards an aggressive phenotype – neuroendocrine prostate cancer or NE-PC. In our study, we used the Simian-Virus 40 (SV-40) T-antigen driven ...